Boster Immunoleader

ELISA/assay

Mouse DLL4 PicoKine ELISA Kit

EK1277

1 x96 well plate

369 USD

Mouse DLL4 PicoKine ELISA Kit

EK1277

369 USD

Sandwich ELISA kit for Quantitative Detection of Mouse DLL4

NSO, S28-P525

1 x96 well plate

156pg/ml-10,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(ng/ml): 2.32; Standard deviation: 0.09; CV(%): 3.9 Sample 2: n=16; Mean(ng/ml): 4.2; Standard deviation: 0.14; CV(%): 3.3 Sample 3: n=16; Mean(ng/ml): 6.12; Standard deviation: 0.26; CV(%): 4.2

Sample 1: n=24; Mean(ng/ml): 2.41; Standard deviation: 0.19; CV(%): 7.9 Sample 2: n=24; Mean(ng/ml): 3.68; Standard deviation: 0.3; CV(%): 8.2 Sample 3: n=24; Mean(ng/ml): 7.35; Standard deviation: 0.54; CV(%): 7.3

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse DLL4 in cell culture supernates, serum and plasma(heparin, EDTA).

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse DLL4 antibody 1 ST0000-10 Lyophilized recombinant mouse DLL4 standard 10ng/tubex2 AR1107 Biotinylated anti- mouse DLL4 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs), in particular to arteries and capillaries, and is involved in vascular development, and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. Mouse DLL4 could activate mouse Notch1 and mouse Notch4. DLL4 acts as a negative regulator of tumor angiogenesis, its blockade results in the striking uncoupling of tumor growth from vessel density, presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it, this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge.

DLL4

Delta-like protein 4

delta-like 4 (Drosophila)

Delta 4 delta 4 precursor Delta ligand 4 delta ligand 4 precursor Delta like 4 Delta like 4 homolog Delta like 4 protein Delta like protein 4 Delta-like 4 (Drosophila) Delta-like protein 4 Delta4 DLL 4 DLL4 DLL4_HUMAN Drosophila Delta homolog 4 hdelta2 Homeobox protein DLL-4 MGC126344 Notch ligand delta 2 Notch ligand DLL4 notch ligand DLL4 precursor XDLL-4

Q9JI71