Boster Immunoleader

ELISA/assay

Human Renin PicoKine ELISA Kit

EK1249

1 x96 well plate

369 USD

Human Renin PicoKine ELISA Kit

EK1249

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Renin

NSO, L67-R406

1 x96 well plate

31.2pg/ml-2000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 353; Standard deviation: 19.8; CV(%): 5.6 Sample 2: n=16; Mean(pg/ml): 643; Standard deviation: 22.51; CV(%): 3.5 Sample 3: n=16; Mean(pg/ml): 1204; Standard deviation: 78.26; CV(%): 6.5

Sample 1: n=24; Mean(pg/ml): 287; Standard deviation: 18.1; CV(%): 6.3 Sample 2: n=24; Mean(pg/ml): 632; Standard deviation: 32.9; CV(%): 5.2 Sample 3: n=24; Mean(pg/ml): 1148; Standard deviation: 81.6; CV(%): 7.1

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Renin in cell culture supernates, serum, plasma(heparin, EDTA) and urine.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Renin antibody 1 ST0000-10 Lyophilized recombinant human Renin standard 10ng/tubex2 AR1107 Biotinylated anti- human Renin antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Renin, also known as an angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system(RAS). This gene is mapped to 1q32.1. Renin's primary function is to cause an increase in blood pressure, leading to restoration of perfusion pressure in the kidneys. It also can catalyze the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. What's more, Renin secretion is also stimulated by sympathetic nervous stimulation, mainly through beta-1 adrenoceptor activation.

REN

Renin

renin

ATP6AP2 ATP6M8-9 ATPase H(+)-transporting lysosomal accessory protein 2 ATPase H(+)-transporting lysosomal-interacting protein 2 Embryonic liver differentiation factor 10 ER-localized type I transmembrane adaptor N14F Renin receptor Renin/prorenin receptor RENR_HUMAN V-ATPase M8.9 subunit Vacuolar ATP synthase membrane sector-associated protein M8-9

P00797