Boster Immunoleader

ELISA/assay

Human Kininogen-1/KNG1 PicoKine ELISA Kit

EK1154

1 x96 well plate

399 USD

Human Kininogen-1/KNG1 PicoKine ELISA Kit

EK1154

399 USD

Sandwich ELISA kit for Quantitative Detection of Human Kininogen-1/KNG1

NSO, Q19-S644

1 x96 well plate

0.78ng/ml-50ng/ml

<20pg/ml

Sample 1: n=16; Mean(ng/ml): 8.5; Standard deviation: 0.323; CV(%): 3.8 Sample 2: n=16; Mean(ng/ml): 14; Standard deviation: 0.658; CV(%): 4.7 Sample 3: n=16; Mean(ng/ml): 28; Standard deviation: 1.54; CV(%): 5.5

Sample 1: n=24; Mean(ng/ml): 10; Standard deviation: 0.43; CV(%): 4.3 Sample 2: n=24; Mean(ng/ml): 19; Standard deviation: 0.969; CV(%): 5.1 Sample 3: n=24; Mean(ng/ml): 35; Standard deviation: 2.17; CV(%): 6.2

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Kininogen-1 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Kininogen-1 antibody 1 ST0000-50 Lyophilized recombinant human Kininogen-1 standard 50ng/tube×2 AR1107 Biotinylated anti- human Kininogen-1 antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Kininogen-1 (KNG1), also known as alpha-2-thiol proteinase inhibitor, Williams-Fitzgerald-Flaujeac factor or the HMWK-kallikrein factor, is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alternative splicing to generate two different proteins – high – molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.

KNG1

Kininogen-1

kininogen 1

Alpha-2-thiol proteinase inhibitor BDK BK BK, included bradykinin bradykinin, included Fitzgerald factor Fitzgerald factor, included Flaujeac factor, included High molecular weight kininogen High molecular weight kininogen, included HMWK HMWK, included Ile-Ser-Bradykinin Kallidin I Kallidin II kininogen 1 KNG KNG1 KNG1_HUMAN LMWK, included Low molecular weight growth-promoting factor Low molecular weight kininogen, included Williams factor, included Williams-Fitzgerald-Flaujeac factor

P01042