Boster Immunoleader

ELISA/assay

Mouse PCSK9 PicoKine ELISA Kit

EK1148

1 x96 well plate

399 USD

Mouse PCSK9 PicoKine ELISA Kit

EK1148

399 USD

Sandwich ELISA kit for Quantitative Detection of Mouse PCSK9

NSO, S156Q-694

1 x96 well plate

62.5pg/ml-4000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 194; Standard deviation: 11.25; CV(%): 5.8 Sample 2: n=16; Mean(pg/ml): 476; Standard deviation: 20.47; CV(%): 4.3 Sample 3: n=16; Mean(pg/ml): 1451; Standard deviation: 66.75; CV(%): 4.6

Sample 1: n=24; Mean(pg/ml): 220; Standard deviation: 20.02; CV(%): 9.1 Sample 2: n=24; Mean(pg/ml): 534; Standard deviation: 33.1; CV(%): 6.2 Sample 3: n=24; Mean(pg/ml): 1608; Standard deviation: 120.6; CV(%): 7.5

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse PCSK9 in cell culture supernates, serum and plasma(heparin, EDTA).

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse PCSK9 antibody 1 ST0000-4 Lyophilized mouse PCSK9 standard 4ng/tubex2 AR1107 Biotinylated anti- mouse PCSK9 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.

PCSK9

Proprotein convertase subtilisin/kexin type 9

proprotein convertase subtilisin/kexin type 9

Convertase subtilisin/kexin type 9 preproprotein FH3 HCHOLA3 Hypercholesterolemia autosomal dominant 3 LDLCQ1 NARC 1 NARC-1 NARC1 Neural apoptosis regulated convertase 1 Neural apoptosis-regulated convertase 1 PC 9 PC9 PCSK 9 PCSK9 PCSK9_HUMAN Proprotein convertase 9 Proprotein convertase PC9 Proprotein convertase subtilisin/kexin type 9 PSEC0052 Subtilisin/kexin like protease PC9 Subtilisin/kexin-like protease PC9

Q80W65