Boster Immunoleader

ELISA/assay

Human PCSK9 PicoKine ELISA Kit

EK1147

1 x96 well plate

369 USD

Human PCSK9 PicoKine ELISA Kit

EK1147

369 USD

Sandwich ELISA kit for Quantitative Detection of Human PCSK9

NSO, S153-Q692

1 x96 well plate

156pg/ml-10,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 1425; Standard deviation: 82.65; CV(%): 5.8 Sample 2: n=16; Mean(pg/ml): 3028; Standard deviation: 193.8; CV(%): 6.4 Sample 3: n=16; Mean(pg/ml): 5769; Standard deviation: 271.1; CV(%): 4.7

Sample 1: n=24; Mean(pg/ml): 1682; Standard deviation: 116.1; CV(%): 6.9 Sample 2: n=24; Mean(pg/ml): 3181; Standard deviation: 232.2; CV(%): 7.3 Sample 3: n=24; Mean(pg/ml): 6226; Standard deviation: 342.43; CV(%): 5.5

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human PCSK9 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human PCSK9 antibody 1 ST0000-10 Lyophilized recombinant human PCSK9 standard 10ng/tubex2 AR1107 Biotinylated anti- human PCSK9 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.

PCSK9

Proprotein convertase subtilisin/kexin type 9

proprotein convertase subtilisin/kexin type 9

Convertase subtilisin/kexin type 9 preproprotein FH3 HCHOLA3 Hypercholesterolemia autosomal dominant 3 LDLCQ1 NARC 1 NARC-1 NARC1 Neural apoptosis regulated convertase 1 Neural apoptosis-regulated convertase 1 PC 9 PC9 PCSK 9 PCSK9 PCSK9_HUMAN Proprotein convertase 9 Proprotein convertase PC9 Proprotein convertase subtilisin/kexin type 9 PSEC0052 Subtilisin/kexin like protease PC9 Subtilisin/kexin-like protease PC9

Q8NBP7