Boster Immunoleader

ELISA/assay

Mouse GDF-15 PicoKine ELISA Kit

EK1134

1 x96 well plate

369 USD

Mouse GDF-15 PicoKine ELISA Kit

EK1134

369 USD

Sandwich ELISA kit for Quantitative Detection of Mouse GDF-15

NSO, S189-A303

1 x96 well plate

15.6pg/ml-1000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 114; Standard deviation: 4.33; CV(%): 3.8 Sample 2: n=16; Mean(pg/ml): 346; Standard deviation: 12.46; CV(%): 3.6 Sample 3: n=16; Mean(pg/ml): 548; Standard deviation: 22.47; CV(%): 4.1

Sample 1: n=24; Mean(pg/ml): 98.2; Standard deviation: 7.37; CV(%): 7.5 Sample 2: n=24; Mean(pg/ml): 359; Standard deviation: 20.10; CV(%): 5.6 Sample 3: n=24; Mean(pg/ml): 579; Standard deviation: 39.37; CV(%): 6.8

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse GDF-15 in cell culture supernates, serum and plasma(heparin, EDTA).

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse GDF-15 antibody 1 ST0000-10 Lyophilized recombinant mouse GDF-15 standard 1ng/tubex2 AR1107 Biotinylated anti- mouse GDF-15 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

GDF-15(Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH, the MIC1 gene is mapped to 19p13.2-p13.1. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF15 showed increased expression and secretion during erythroblast maturation. GDF15 functions as an antiinflammatory cytokine by directly interfering with chemokine signaling and integrin activation.

GDF15

Growth/differentiation factor 15

growth differentiation factor 15

Growth/differentiation factor 15 Macrophage inhibitory cytokine 1 MIC 1 NAG-1 NRG-1 NSAID-activated gene 1 protein NSAID-regulated gene 1 protein PDF PLAB Placental bone morphogenetic protein Placental TGF-beta Prostate differentiation factor PROSTATE-DERIVED FACTOR PTGFB

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