Boster Immunoleader

ELISA/assay

Human TNFRSF9/4-1BB PicoKine ELISA Kit

EK0988

1 x96 well plate

369 USD

Human TNFRSF9/4-1BB PicoKine ELISA Kit

EK0988

369 USD

Sandwich ELISA kit for Quantitative Detection of Human TNFRSF9/4-1BB

NSO, L24-Q186

1 x96 well plate

31.2pg/ml-2000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 241; Standard deviation: 8.9; CV(%): 3.7 Sample 2: n=16; Mean(pg/ml): 668; Standard deviation: 34; CV(%): 5.1 Sample 3: n=16; Mean(pg/ml): 1134; Standard deviation: 48.8; CV(%): 4.3

Sample 1: n=24; Mean(pg/ml): 224; Standard deviation: 11; CV(%): 4.9 Sample 2: n=24; Mean(pg/ml): 735; Standard deviation: 45.57; CV(%): 6.2 Sample 3: n=24; Mean(pg/ml): 1268; Standard deviation: 69.8; CV(%): 5.5

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human TNFRSF9 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human TNFRSF9 antibody 1 ST0000-10 Lyophilized recombinant human TNFRSF9 standard 10ng/tubex2 AR1107 Biotinylated anti- human TNFRSF9 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

CD137 is a member of the tumor necrosis factor(TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9(TNFRSF9), 4-1BB and induced by lymphocyte activation(ILA). CD137 gene was localized to chromosome 1p36.Members of this receptor family and their structurally related ligands are important regulators of a wide variety of physiological processes and play an especially important role in the regulation of immune responses. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

TNFRSF9

Tumor necrosis factor receptor superfamily member 9

tumor necrosis factor receptor superfamily, member 9

4-1BB 4-1BB ligand receptor CD137 CD137 antigen CDw137 Homolog of mouse 4 1BB ILA Induced by lymphocyte activation (ILA) Interleukin activated receptor homolog of mouse Ly63 Receptor protein 4 1BB T-cell antigen 4-1BB homolog T-cell antigen ILA TNFRSF9 TNR9_HUMAN Tumor necrosis factor receptor superfamily member 9

Q07011