product summary
request information :
company name :
Boster Immunoleader
product type :
ELISA/assay
product name :
Human TGF-beta 2 PicoKine ELISA Kit
catalog :
EK0981
quantity :
1 x96 well plate
price :
369 USD
product information
Product Name :
Human TGF-beta 2 PicoKine ELISA Kit
Catalog Number :
EK0981
Price :
369 USD
Description short :
Sandwich ELISA kit for Quantitative Detection of Human TGF-beta 2
immunogen :
NSO, A303-S414
Pack Size :
1 x96 well plate
Assay Range :
31.2pg/ml-2000pg/ml
Sensitivity :
<10pg/ml
Intra-Assay Precision :
Sample 1: n=16; Mean(pg/ml): 221; Standard deviation: 13.7; CV(%): 6.2 Sample 2: n=16; Mean(pg/ml): 564; Standard deviation: 13.6; CV(%): 5.6 Sample 3: n=16; Mean(pg/ml): 1145; Standard deviation: 46.9; CV(%): 4.1
Inter-Assay Precision :
Sample 1: n=24; Mean(pg/ml): 236; Standard deviation: 15.8; CV(%): 6.7 Sample 2: n=24; Mean(pg/ml): 576; Standard deviation: 33.41; CV(%): 5.8 Sample 3: n=24; Mean(pg/ml): 1095; Standard deviation: 70.1; CV(%): 6.4
Cross Reactivity :
There is no detectable cross-reactivity with other relevant proteins.
Storage :
Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Sample Type :
This kit is used for quantitative detection of activated human TGF-beta 2 in cell culture supernates, serum and plasma(heparin, EDTA, citrate).
Reactivity :
Human
Kit Components :
Catalog number Description Quantity - 96-well plate precoated with anti- human TGF-beta 2 antibody 1 ST0000-10 Lyophilized recombinant human TGF-beta 2 standard 10ng/tubex2 AR1107 Biotinylated anti- human TGF-beta 2 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml
Background :
Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured human anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
Gene Name :
TGFB2
Protein Name :
Transforming growth factor beta-2
Gene Full Name :
transforming growth factor, beta 2
Synonyms :
BSC 1 cell growth inhibitor BSC-1 cell growth inhibitor Cetermin G-TSF Glioblastoma derived T cell suppressor factor Glioblastoma-derived T-cell suppressor factor Polyergin TGF beta2 TGF-beta-2 TGFB2 TGFB2_HUMAN Transforming growth factor beta-2 Transforming growth factor, beta 2
Uniprot IDs :
P61812
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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