Boster Immunoleader

ELISA/assay

Human Progranulin PicoKine ELISA Kit

EK0973

1 x96 well plate

369 USD

Human Progranulin PicoKine ELISA Kit

EK0973

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Progranulin

NSO, T18-L593

1 x96 well plate

1.56ng/ml-100ng/ml

<50pg/ml

Sample 1: n=16; Mean(ng/ml): 15.4; Standard deviation: 0.986; CV(%): 6.4 Sample 2: n=16; Mean(ng/ml): 37.7; Standard deviation: 2; CV(%): 5.3 Sample 3: n=16; Mean(ng/ml): 56; Standard deviation: 2.69; CV(%): 4.8

Sample 1: n=24; Mean(ng/ml): 13.6; Standard deviation: 1.02; CV(%): 7.5 Sample 2: n=24; Mean(ng/ml): 32.8; Standard deviation: 2.69; CV(%): 8.2 Sample 3: n=24; Mean(ng/ml): 61; Standard deviation: 4.76; CV(%): 7.8

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Progranulin in cell culture supernates, serum, plasma(heparin, EDTA), saliva, urine and human milk.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Progranulin antibody 1 ST0000-10 Lyophilized recombinant human Progranulin standard 100ng/tubex2 AR1107 Biotinylated anti- human Progranulin antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Granulin, also known as Proepithelin(PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

GRN

Granulins

granulin

Acrogranin CLN11 GEP GP88 Granulin A Granulin B Granulin C Granulin D Granulin E Granulin epithelin Granulin F Granulin G Granulin-7 Granulins GRN GRN_HUMAN PC cell derived growth factor PCDGF PEPI PGRN Proepithelin Progranulin

P28799