Boster Immunoleader

ELISA/assay

Human TNFRSF16/NGFR PicoKine ELISA Kit

EK0972

1 x96 well plate

369 USD

Human TNFRSF16/NGFR PicoKine ELISA Kit

EK0972

369 USD

Sandwich ELISA kit for Quantitative Detection of Human TNFRSF16/NGFR

sf21, K29-N250

1 x96 well plate

62.5pg/ml-4000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 81; Standard deviation: 4.21; CV(%): 5.2 Sample 2: n=16; Mean(pg/ml): 330; Standard deviation: 21.45; CV(%): 6.5 Sample 3: n=16; Mean(pg/ml): 1560; Standard deviation: 90.48; CV(%): 5.8

Sample 1: n=24; Mean(pg/ml): 85; Standard deviation: 5.27; CV(%): 6.2 Sample 2: n=24; Mean(pg/ml): 360; Standard deviation: 27; CV(%): 7.5 Sample 3: n=24; Mean(pg/ml): 1350; Standard deviation: 90.45; CV(%): 6.7

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human TNFRSF16 in cell culture supernates, serum and plasma(heparin, EDTA, citrate).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human TNFRSF16 antibody 1 ST0000-10 Lyophilized recombinant human TNFRSF16 standard 10ng/tube×2 AR1107 Biotinylated anti- human TNFRSF16 antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) because of its ability to bind at low affinity not only to NGF, but also other neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5. The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias. The neurotrophin receptor p75(NTR), a tumor necrosis factor receptor superfamily member expressed in hepatic stellate cells after fibrotic and cirrhotic liver injury in humans, is a regulator of liver repair. In mice, depletion of p75(NTR) exacerbated liver pathology and inhibited hepatocyte proliferation in vivo. In addition, it is showed that neurotrophins activate p75(NTR) to induce apoptosis through the induction of the sphingomyelin (SM) cycle and increased production of ceramide. Overexpression of p75(NTR) is also found to activate the SM pathway.

NGFR

Tumor necrosis factor receptor superfamily member 16

nerve growth factor receptor

CD271 CD271 antigen Gp80 LNGFR Gp80 LNGFR Gp80-LNGFR Low affinity nerve growth factor receptor Low affinity nerve growth factor receptor Low affinity neurotrophin receptor p75NTR Low affinity neurotrophin receptor p75NTR Low-affinity nerve growth factor receptor Nerve growth factor receptor Nerve growth factor receptor TNFR superfamily member 16 NGF receptor NGF receptor NGFR p75 ICD p75 ICD p75 Neurotrophin receptor p75 NTR p75(NTR) p75NTR TNFR Superfamily Member 16 TNFRSF16 TNR16_HUMAN Tumor necrosis factor receptor superfamily member 16

P08138