Boster Immunoleader

ELISA/assay

Rat RAGE PicoKine ELISA Kit

EK0971

1 x96 well plate

369 USD

Rat RAGE PicoKine ELISA Kit

EK0971

369 USD

Sandwich ELISA kit for Quantitative Detection of Rat RAGE

NSO, Q24-A342

1 x96 well plate

78pg/ml-5,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 592; Standard deviation: 36.1; CV(%): 6.1 Sample 2: n=16; Mean(pg/ml): 1590; Standard deviation: 84.27; CV(%): 5.3 Sample 3: n=16; Mean(pg/ml): 3161; Standard deviation: 180.2; CV(%): 5.7

Sample 1: n=24; Mean(pg/ml): 633; Standard deviation: 46.21; CV(%): 7.3 Sample 2: n=24; Mean(pg/ml): 1386; Standard deviation: 88.71; CV(%): 6.4 Sample 3: n=24; Mean(pg/ml): 3155; Standard deviation: 227.16; CV(%): 7.2

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of rat RAGE in cell culture supernates, serum and plasma(heparin, EDTA).

Rat

Catalog number Description Quantity - 96-well plate precoated with anti- rat RAGE antibody 1 ST0000-10 Lyophilized recombinant rat RAGE standard 10ng/tubex2 AR1107 Biotinylated anti- rat RAGE antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as “AGER”. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B(NF-kappaB).

AGER

Advanced glycosylation end product-specific receptor

advanced glycosylation end product-specific receptor

Advanced glycosylation end product specific receptor Advanced glycosylation end product-specific receptor Ager DAMA 358M23.4 LE 9211 A antigen MAPK MAK MRK overlapping kinase MGC22357 MOK OTTHUMP00000174885 RAGE 1 RAGE isoform NtRAGE-delta RAGE isoform sRAGE-delta RAGE_HUMAN RAGE1 Receptor for advanced glycation end products receptor for advanced glycation end-products variant 20 Receptor for advanced glycosylation end products Renal tumor antigen Renal tumor antigen Renal tumor antigen 1

Q63495