Boster Immunoleader

ELISA/assay

Human MICB PicoKine ELISA Kit

EK0963

1 x96 well plate

399 USD

Human MICB PicoKine ELISA Kit

EK0963

399 USD

Sandwich ELISA kit for Quantitative Detection of Human MICB

NSO, A23-G298

1 x96 well plate

62.5pg/ml-4000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 317; Standard deviation: 20.3; CV(%): 6.4 Sample 2: n=16; Mean(pg/ml): 1323; Standard deviation: 68.8; CV(%): 5.2 Sample 3: n=16; Mean(pg/ml): 2334; Standard deviation: 100.4; CV(%): 4.3

Sample 1: n=24; Mean(pg/ml): 426; Standard deviation: 32.4; CV(%): 7.6 Sample 2: n=24; Mean(pg/ml): 1518; Standard deviation: 97.2; CV(%): 6.4 Sample 3: n=24; Mean(pg/ml): 2544; Standard deviation: 150.1; CV(%): 5.9

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human MICB in cell culture supernates, serum and plasma(heparin, EDTA) .

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human MICB antibody 1 ST0000-10 Lyophilized recombinant human MICB standard 10ng/tubex2 AR1107 Biotinylated anti- human MICB antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

MHC class I polypeptide-related sequence B, also called MICB is a protein that in humans is encoded by the MICB gene. The MICB gene is mapped to 6p21.33. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer(NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. It seems to have no role in antigen presentation. This gene acts as a stress-induced self-antigen that is recognized by gamma delta T cells. It is the ligand for the KLRK1/NKG2D receptor and binds to KLRK1 leads to cell lysis.

MICB

MHC class I polypeptide-related sequence B

MHC class I polypeptide-related sequence B

MHC class I chain related protein B MHC class I like molecule PERB11.2 IMX MHC class I mic B antigen MHC class I polypeptide related sequence B MHC class I polypeptide-related sequence B MIC B MIC-B MICB MICB_HUMAN PERB11.2 Stress inducible class I homolog

Q29980