Boster Immunoleader

ELISA/assay

Human Furin PicoKine ELISA Kit

EK0916

1 x96 well plate

369 USD

Human Furin PicoKine ELISA Kit

EK0916

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Furin

NSO, D108-E715

1 x96 well plate

312pg/ml-20,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(ng/ml): 1.9; Standard deviation: 0.091; CV(%): 4.8 Sample 2: n=16; Mean(ng/ml): 8.8; Standard deviation: 0.493; CV(%): 5.6 Sample 3: n=16; Mean(ng/ml): 15.7; Standard deviation: 0.942; CV(%): 6

Sample 1: n=24; Mean(ng/ml): 2.3; Standard deviation: 0.122; CV(%): 5.3 Sample 2: n=24; Mean(ng/ml): 9.2; Standard deviation: 0.589; CV(%): 6.4 Sample 3: n=24; Mean(ng/ml): 17.4; Standard deviation: 1.27; CV(%): 7.3

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of Human Furin in cell culture supernates, tissue homogenates and cell lysates.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Furin antibody 1 ST0000-20 Lyophilized recombinant human Furin standard 20ng/tubex2 AR1107 Biotinylated anti- human Furin antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance

FURIN

Furin

furin (paired basic amino acid cleaving enzyme)

Dibasic processing enzyme Dibasic-processing enzyme FES upstream region FUR FURIN Furin membrane associated receptor protein FURIN_HUMAN PACE Paired basic amino acid residue cleaving enzyme Paired basic amino acid residue-cleaving enzyme PCSK3 Proprotein convertase subtilisin/kexin type 3 SPC1

P09958