Boster Immunoleader

ELISA/assay

Human Aggrecan PicoKine ELISA Kit

EK0909

1 x96 well plate

369 USD

Human Aggrecan PicoKine ELISA Kit

EK0909

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Aggrecan

NSO, V20-G675

1 x96 well plate

1.56ng/ml-100ng/ml

<50pg/ml

Sample 1: n=16; Mean(ng/ml): 15; Standard deviation: 0.825; CV(%): 5.5 Sample 2: n=16; Mean(ng/ml): 42; Standard deviation: 1.806; CV(%): 4.3 Sample 3: n=16; Mean(ng/ml): 74; Standard deviation: 4.588; CV(%): 6.2

Sample 1: n=24; Mean(ng/ml): 16; Standard deviation: 0.944; CV(%): 5.9 Sample 2: n=24; Mean(ng/ml): 41; Standard deviation: 2.255; CV(%): 5.5 Sample 3: n=24; Mean(ng/ml): 72; Standard deviation: 4.824; CV(%): 6.7

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Aggrecan in cell culture supernates, serum and urine.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Aggrecan antibody 1 ST0000-10 Lyophilized recombinant human Aggrecan standard 100ng/tube×2 AR1107 Biotinylated anti- human Aggrecan antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Aggrecan, also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. It is a critical component for cartilage structure and the function of joints. Aggrecan provides intervertebral disc and cartilage with the ability to resist compressive loads. The localized high concentrations of aggrecan provide the osmotic properties necessary for normal tissue function with the GAGs producing the swelling pressure that counters compressive loads on the tissue. This functional ability is dependent on a high GAG/aggrecan concentration being present in the tissue extracellular matrix. Also, Aggrecan plays an important role in the organization of the extracellular spaces between neurons in the brain.

ACAN

Aggrecan core protein

aggrecan

ACAN AGC 1 AGC1 AGCAN Aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) Aggrecan 1 Aggrecan core protein Aggrecan proteoglycan Aggrecan structural proteoglycan of cartilage Aggrecan1 ATEGQV Cartilage specific proteoglycan core protein Chondroitin sulfate proteoglycan 1 Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122 Chondroitin sulfate proteoglycan core protein 1 CSPG 1 CSPG1 CSPGCP JSCATE Large aggregating proteoglycan mcspg mgsk16 MSK 16 MSK16 SEDK

P16112