Boster Immunoleader

ELISA/assay

Human TNFSF11/RANKL PicoKine ELISA Kit

EK0842

1 x96 well plate

369 USD

Human TNFSF11/RANKL PicoKine ELISA Kit

EK0842

369 USD

Sandwich ELISA kit for Quantitative Detection of Human TNFSF11/RANKL

NSO, G64-D245

1 x96 well plate

78pg/ml-5000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 624; Standard deviation: 20.6; CV(%): 3.3 Sample 2: n=16; Mean(pg/ml): 1302; Standard deviation: 66.4; CV(%): 5.1 Sample 3: n=16; Mean(pg/ml): 2684; Standard deviation: 123.5; CV(%): 4.6

Sample 1: n=24; Mean(pg/ml): 714; Standard deviation: 28.56; CV(%): 4 Sample 2: n=24; Mean(pg/ml): 1428; Standard deviation: 92.82; CV(%): 6.5 Sample 3: n=24; Mean(pg/ml): 2710; Standard deviation: 154.5; CV(%): 5.7

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human TNFSF11 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human TNFSF11 antibody 1 ST0000-10 Lyophilized recombinant human TNFSF11 standard 10ng/tubex2 AR1107 Biotinylated anti- human TNFSF11 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Receptor activator of nuclear factor kappa-B ligand(RANKL), also known as tumor necrosis factor ligand superfamily member 11(TNFSF11), is a protein that in humans is encoded by the TNFSF11 gene. This gene encodes a member of the tumor necrosis factor(TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This gene is mapped to chromosome13q14.11. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. This gene may play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

TNFSF11

Tumor necrosis factor ligand superfamily member 11

tumor necrosis factor (ligand) superfamily, member 11

CD254 CD254 antigen hRANKL2 ODF OPGL OPTB2 Osteoclast differentiation factor Osteoprotegerin ligand RANKL receptor activator of nuclear factor kappa B ligand Receptor activator of nuclear factor kappa-B ligand sOdf soluble form TNF-related activation-induced cytokine TNF11_HUMAN Tnfsf11 TRANCE tumor necrosis factor (ligand) superfamily, member 11 Tumor necrosis factor ligand superfamily member 11

O14788