Boster Immunoleader

ELISA/assay

Human Diablo/SMAC PicoKine ELISA Kit

EK0838

1 x96 well plate

369 USD

Human Diablo/SMAC PicoKine ELISA Kit

EK0838

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Diablo/SMAC

E.coli, A56-D239

1 x96 well plate

31.2pg/ml-2000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 112; Standard deviation: 6.27; CV(%): 5.6 Sample 2: n=16; Mean(pg/ml): 545; Standard deviation: 23.98; CV(%): 4.4 Sample 3: n=16; Mean(pg/ml): 1134; Standard deviation: 58.97; CV(%): 5.2

Sample 1: n=24; Mean(pg/ml): 129; Standard deviation: 7.99; CV(%): 6.2 Sample 2: n=24; Mean(pg/ml): 577; Standard deviation: 40.97; CV(%): 7.1 Sample 3: n=24; Mean(pg/ml): 1133; Standard deviation: 77.04; CV(%): 6.8

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Diablo in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Diablo antibody 1 ST0000-10 Lyophilized recombinant human Diablo standard 10ng/tubex2 AR1107 Biotinylated anti- human Diablo antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Diablo homolog, mitochondrial, also known as second mitochondria-derived activator of caspases(SMAC), is a protein that in humans is encoded by the DIABLO gene(direct IAP binding protein with low pI). It is mapped to 12q24.31. DIABLO can bind mammalian IAP homolog A(MIHA, or API3) and can also interact with MIHB, MIHC, and OpIAP, the baculoviral IAP. This gene encodes an inhibitor of apoptosis protein(IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Over expression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64.

DIABLO

Diablo homolog, mitochondrial

diablo, IAP-binding mitochondrial protein

DFNA64 DIABLO diablo homolog, mitochondrial diablo, IAP-binding mitochondrial protein DIABLO-S direct IAP-binding protein with low pI mitochondrial Smac protein second mitochondria-derived activator of caspase SMAC3

Q9NR28