Boster Immunoleader

ELISA/assay

Human Kallikrein-6 PicoKine ELISA Kit

EK0818

1 x96 well plate

369 USD

Human Kallikrein-6 PicoKine ELISA Kit

EK0818

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Kallikrein-6

NSO, L22-K244

1 x96 well plate

78pg/ml-5,000pg/ml

<3pg/ml

Sample 1: n=16; Mean(pg/ml): 545; Standard deviation: 37.61; CV(%): 6.9 Sample 2: n=16; Mean(pg/ml): 1711; Standard deviation: 80.42; CV(%): 4.7 Sample 3: n=16; Mean(pg/ml): 2903; Standard deviation: 168.4; CV(%): 5.8

Sample 1: n=24; Mean(pg/ml): 721; Standard deviation: 55.52; CV(%): 7.7 Sample 2: n=24; Mean(pg/ml): 1927; Standard deviation: 104.1; CV(%): 5.4 Sample 3: n=24; Mean(pg/ml): 3120; Standard deviation: 196.6; CV(%): 6.3

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Kallikrein-6 in cell culture supernates, cell lysates, serum, plasma(heparin, EDTA) and tissue homogenates.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Kallikrein-6 antibody 1 ST0000-10 Lyophilized recombinant human Kallikrein-6 standard 10ng/tubex2 AR1107 Biotinylated anti- human Kallikrein-6 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.

KLK6

Kallikrein-6

kallikrein-related peptidase 6

Kallikrein-6 Klk6 KLK6_HUMAN Neurosin Protease M Serine protease 18 Serine protease 9 SP59 Zyme

Q92876