Boster Immunoleader

ELISA/assay

Mouse MER/MERTK PicoKine ELISA Kit

EK0811

1 x96 well plate

399 USD

Mouse MER/MERTK PicoKine ELISA Kit

EK0811

399 USD

Sandwich ELISA kit for Quantitative Detection of Mouse MER/MERTK

sf21, E23-F498

1 x96 well plate

78pg/ml-5000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 568; Standard deviation: 25.56; CV(%): 4.5 Sample 2: n=16; Mean(pg/ml): 1965; Standard deviation: 102.18; CV(%): 5.2 Sample 3: n=16; Mean(pg/ml): 3223; Standard deviation: 183.7; CV(%): 5.7

Sample 1: n=24; Mean(pg/ml): 790; Standard deviation: 45.82; CV(%): 5.8 Sample 2: n=24; Mean(pg/ml): 2135; Standard deviation: 140.91; CV(%): 6.6 Sample 3: n=24; Mean(pg/ml): 3632; Standard deviation: 257.9; CV(%): 7.1

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse MER in cell culture supernates, cell lysates, tissue homogenates and serum.

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse MER antibody 1 ST0000-10 Lyophilized recombinant mouse MER standard 10ng/tubex2 AR1107 Biotinylated anti- mouse MER antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium(RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors(TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

MERTK

Tyrosine-protein kinase Mer

c-mer proto-oncogene tyrosine kinase

C mer c mer proto oncogene tyrosine kinase MER receptor tyrosine kinase Mertk MERTK_HUMAN Proto-oncogene c-Mer Receptor tyrosine kinase MerTK RP38 STK kinase Tyrosine-protein kinase Mer

Q60805