Boster Immunoleader

ELISA/assay

Human ESM1/Endocan PicoKine ELISA Kit

EK0752

1 x96 well plate

333 USD

Human ESM1/Endocan PicoKine ELISA Kit

EK0752

333 USD

Sandwich ELISA kit for Quantitative Detection of Human ESM1/Endocan

NSO, W20-R184

1 x96 well plate

31.2pg/ml-2000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 98; Standard deviation: 5; CV(%): 5.1 Sample 2: n=16; Mean(pg/ml): 815; Standard deviation: 35; CV(%): 4.3 Sample 3: n=16; Mean(pg/ml): 1324; Standard deviation: 48.98; CV(%): 3.7

Sample 1: n=24; Mean(pg/ml): 153; Standard deviation: 9.3; CV(%): 6.1 Sample 2: n=24; Mean(pg/ml): 968; Standard deviation: 51.3; CV(%): 5.3 Sample 3: n=24; Mean(pg/ml): 1560; Standard deviation: 71.76; CV(%): 4.6

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human ESM1 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human ESM1 antibody 1 ST0000-10 Lyophilized recombinant human ESM1 standard 10ng/tubex2 AR1107 Biotinylated anti- human ESM1 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Endothelial cell-specific molecule 1, also known as Endocan, is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis by independent teams. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF(vascular endothelial growth factor) or FGF-2 (fibroblast growth factor 2).

ESM1

Endothelial cell-specific molecule 1

endothelial cell-specific molecule 1

Endothelial cell-specific molecule 1 ESM-1 Esm1 ESM1_HUMAN

Q9NQ30