Boster Immunoleader

ELISA/assay

Human IL7R/CD127 PicoKine ELISA Kit

EK0713

1 x96 well plate

369 USD

Human IL7R/CD127 PicoKine ELISA Kit

EK0713

369 USD

Sandwich ELISA kit for Quantitative Detection of Human IL7R/CD127

NSO, E21-I262

1 x96 well plate

312pg/ml-20,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(ng/ml): 2.8; Standard deviation: 0.168; CV(%): 6 Sample 2: n=16; Mean(ng/ml): 8; Standard deviation: 0.36; CV(%): 4.5 Sample 3: n=16; Mean(ng/ml): 14.3; Standard deviation: 0.815; CV(%): 5.7

Sample 1: n=24; Mean(ng/ml): 3.4; Standard deviation: 0.245; CV(%): 7.2 Sample 2: n=24; Mean(ng/ml): 9.1; Standard deviation: 0.51; CV(%): 5.6 Sample 3: n=24; Mean(ng/ml): 16.2; Standard deviation: 1.07; CV(%): 6.6

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human IL7R in cell culture supernates and serum.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human IL7R antibody 1 ST0000-20 Lyophilized recombinant human IL7R standard 20ng/tubex2 AR1107 Biotinylated anti- human IL7R antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

The interleukin-7 receptor(IL7R) is a protein found on the surface of cells. It is mapped to 5p13.2. The protein encoded by this gene is a receptor for interleukine 7(IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain(IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. IL7R has been shown to play a critical role in the development of immune cells called lymphocytes-specifically in a process known as V(D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation. What's more, IL7R antagonism is efficacious in treatment of EAE through its effects on Th17 cells and is a potential treatment for MS.

IL7R

Interleukin-7 receptor subunit alpha

interleukin 7 receptor

CD 127 CD127 CD127 antigen CDw127 IL 7R alpha IL 7R IL-7 receptor subunit alpha IL-7R subunit alpha IL-7R-alpha IL-7RA IL7R IL7RA IL7RA_HUMAN IL7Ralpha ILRA Interleukin 7 receptor alpha chain Interleukin 7 receptor Interleukin 7 receptor isoform H5 6 Interleukin-7 receptor subunit alpha

P16871