Boster Immunoleader

ELISA/assay

Human Cathepsin D PicoKine ELISA Kit

EK0672

1 x96 well plate

430 USD

Human Cathepsin D PicoKine ELISA Kit

EK0672

430 USD

Sandwich ELISA kit for Quantitative Detection of Human Cathepsin D

NSO, L21-L412

1 x96 well plate

156pg/ml-10,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(ng/ml): 1.24; Standard deviation: 0.035; CV(%): 2.8 Sample 2: n=16; Mean(ng/ml): 3.37; Standard deviation: 0.108; CV(%): 3.2 Sample 3: n=16; Mean(ng/ml): 6.73; Standard deviation: 0.236; CV(%): 3.5

Sample 1: n=24; Mean(ng/ml): 1.38; Standard deviation: 0.047; CV(%): 3.4 Sample 2: n=24; Mean(ng/ml): 3.51; Standard deviation: 0.130; CV(%): 3.7 Sample 3: n=24; Mean(ng/ml): 6.82; Standard deviation: 0.28; CV(%): 4.1

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Cathepsin D in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Cathepsin D antibody 1 ST0000-10 Lyophilized recombinant human Cathepsin D standard 10ng/tubex2 AR1107 Biotinylated anti- human Cathepsin D antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

CTSD

Cathepsin D

cathepsin D

CATD_HUMAN Cathepsin D heavy chain Ceroid lipofuscinosis neuronal 10 CLN10 CPSD ctsd Lysosomal aspartyl protease

P07339