Boster Immunoleader

ELISA/assay

Mouse TNFR2 PicoKine ELISA Kit

EK0531

1 x96 well plate

369 USD

Mouse TNFR2 PicoKine ELISA Kit

EK0531

369 USD

Sandwich ELISA kit for Quantitative Detection of Mouse TNFR2

NSO, V23-G258

1 x96 well plate

15.6pg/ml-1000pg/ml

<1pg/ml

Sample 1: n=16; Mean(pg/ml): 92; Standard deviation: 4.6; CV(%): 5 Sample 2: n=16; Mean(pg/ml): 263; Standard deviation: 11.57; CV(%): 4.4 Sample 3: n=16; Mean(pg/ml): 492; Standard deviation: 27.6; CV(%): 5.6

Sample 1: n=24; Mean(pg/ml): 104; Standard deviation: 5.4; CV(%): 5.2 Sample 2: n=24; Mean(pg/ml): 253; Standard deviation: 14.67; CV(%): 5.8 Sample 3: n=24; Mean(pg/ml): 527; Standard deviation: 32.2; CV(%): 6.1

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse TNFR2 in cell culture supernates and serum.

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse TNFR2 antibody 1 ST0000-10 Lyophilized recombinant mouse TNFR2 standard 10ng/tubex2 AR1107 Biotinylated anti- mouse TNFR2 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Tumor necrosis factor receptor 2(TNFR2) is one of receptors of TNF. TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors(TNFRs), TNFR1 and TNFR2. The genes for TNFR1, a 55-kDa protein, and TNFR2, a 70-kDa protein, have been mapped to human chromosomes 12(12pter-cen) and 1(1pter-p32), respectively. TNFR2 was induced on glomerular endothelial cells of nephritic kidneys, and TNFR2 expression on intrinsic cells, but not leukocytes, was essential for glomerulonephritis and glomerular complement deposition. TNFR1 promotes systemic immune responses and renal T cell death, while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury. Therefore, therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis.

TNFRSF1B

Tumor necrosis factor receptor superfamily member 1B

tumor necrosis factor receptor superfamily, member 1B

CD120b Etanercept p75 p80 TNF alpha receptor TBP2 TBPII TNF R2 TNFBR TNFR-II TNFR2 TNFRII Tumor necrosis factor binding protein 2 Tumor necrosis factor receptor 2 Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 1b, membrane form Tumor necrosis factor receptor type II

P25119