Boster Immunoleader

ELISA/assay

Human MMP-7 PicoKine ELISA Kit

EK0463

1 x96 well plate

430 USD

Human MMP-7 PicoKine ELISA Kit

EK0463

430 USD

Sandwich ELISA kit for Quantitative Detection of Human MMP-7

NSO, L18-K267

1 x96 well plate

156pg/ml-10,000pg/ml

<6pg/ml

Sample 1: n=16; Mean(ng/ml): 1.37; Standard deviation: 0.073; CV(%): 5.3 Sample 2: n=16; Mean(ng/ml): 4.75; Standard deviation: 0.2; CV(%): 4.2 Sample 3: n=16; Mean(ng/ml): 6.34; Standard deviation: 0.241; CV(%): 3.8

Sample 1: n=24; Mean(ng/ml): 1.25; Standard deviation: 0.078; CV(%): 6.2 Sample 2: n=24; Mean(ng/ml): 4.81; Standard deviation: 0.284; CV(%): 5.9 Sample 3: n=24; Mean(ng/ml): 6.53; Standard deviation: 0.438; CV(%): 6.7

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human MMP-7 in cell culture supernates, serum, plasma(heparin), saliva and urine.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human MMP-7 antibody 1 ST0000-10 Lyophilized recombinant human MMP-7 standard 10ng/tubex2 AR1107 Biotinylated anti- human MMP-7 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Matrix metalloproteinase-7(MMP-7) previously called putative metalloproteinase I(PUMP1) or matrilysin. The PUMP1 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The PUMP I protein has 267 amino acids and is significantly shorter than stromelysin or collagenase(477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. Matrilysin, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, matrilysin mRNA is regulated in a specific and distinct manner in normal and malignant tissues. Matrilysin has been shown to correlate with nodal or distant metastasis in colorectal carcinomas; however, its implication in early invasive colorectal carcinomas has not been determined.1 Matrilysin is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.

MMP7

Matrilysin

matrix metallopeptidase 7 (matrilysin, uterine)

Matrilysin Matrin Matrix metalloproteinase 7 Matrix metalloproteinase-7 MMP-7 MMP7 MMP7_HUMAN MPSL1 Pump 1 protease Pump-1 protease PUMP1 Uterine metalloproteinase

P09237