product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Biotinylated Human SLAMF5 (C-6His-Avi)
catalog :
CY63
quantity :
20 ug;100 ug
price :
302 USD
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CY63
Product Name :
Biotinylated Human SLAMF5 (C-6His-Avi)
Product Type :
protein
Accession Number :
Q9UIB8
Size :
20 ug;100 ug
List Price :
302 USD
sku :
CY63-20ug
Size option :
20ug;100ug
Product Description :
Biotinylated Recombinant Human SLAM Family Member 5 is produced by our Mammalian expression system and the target gene encoding Lys22-Arg220 is expressed with a 6His, Avi tag at the C-terminus.
Expression :
Human Cells
Background :
SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature human CD84 consists of a 204 amino acid (aa) extracellular domain (ECD) with two Iglike domains,a 21 aa transmembrane segment, and a 99 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs (ITSMs). CD84 exhibits homophilic binding which is mediated by the N-terminal Ig-like domain. Ligation induces tyrosine phosphorylation in the cytoplasmic ITSMs which then recruit the signaling adaptor molecules SAP (SLAM-associated protein) and EAT-2(EWS/Fli1-activated transcript 2).CD84 signaling inhibits Fc epsilon RI-induced mast cell activation but enhances platelet activation. LPS-induced macrophage activation,T cell proliferation and IFN-γproduction, and the interactions between T cells and B cells that are required for germinal center formation.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Packaging :
Ambient
ALTnames :
SLAM family member 5; Cell surface antigen MAX.3; Hly9-beta; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; CD84; SLAMF5
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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