product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Biotinylated Human TIGIT (C-6His-Avi)
catalog :
CY13
quantity :
20 ug;100 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CY13
Product Name :
Biotinylated Human TIGIT (C-6His-Avi)
Product Type :
protein
Accession Number :
Q495A1
Size :
20 ug;100 ug
List Price :
288
sku :
CY13-20ug
Size option :
20ug;100ug
Product Description :
Biotinylated Recombinant Human T cell Immunoreceptor with Ig and ITIM domains is produced by our Mammalian expression system and the target gene encoding Met22-Pro141 is expressed with a 6His, Avi tag at the C-terminus.
Expression :
Human Cells
Background :
T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the CD28 family within the Ig superfamily of proteins. TIGIT is expressed on NK cells and subsets of activated, memory and regulatory T cells, and particularly on follicular helper T cells within secondary lymphoid organs. It binds to CD155 and Nectin-2 that appear on dendritic cells (DC) and endothelium. Ligation of TIGIT on T cells down-regulates TCR-mediated activation and subsequent proliferation, while NK cell TIGIT ligation blocks NK cell cytotoxicity. Through CD155 and Nectin-2, which also interact with DNAM-1/CD226 and CD96/Tactile, TIGIT is part of an interacting network of Ig superfamily members that may augment or oppose each other. In particular, TIGIT binding to CD155 can antagonize the effects of DNAM1.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Packaging :
Ambient
ALTnames :
T-cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3; TIGIT; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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