product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Biotinylated Recombinant Human EpCAM (C-6His-Avi)
catalog :
CY03
quantity :
20 ug;100 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CY03
Product Name :
Biotinylated Recombinant Human EpCAM (C-6His-Avi)
Product Type :
protein
Accession Number :
AAH14785.1
Size :
20 ug;100 ug
List Price :
288
sku :
CY03-20ug
Size option :
20ug;100ug
Product Description :
Biotinylated Recombinant Human Epithelial Cell Adhesion Molecule is produced by our Mammalianexpression system and the target gene encoding Gln24-Lys265 is expressed with a 6His, Avitag at the C-terminus.
Expression :
Human 293 Cells
Background :
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein that belongs to the EPCAM family. EpCAM is composed of an extracellular domain with one thyroglobulin type-1 domain, a transmembrane domain and a cytoplasmic domain. EpCAM is found on the surface of adenocarcinoma, but not on mesodermal or neural cell membranes. The EpCAM molecule has been shown to function as a homophilic Ca2+ independent adhesion molecule. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium as an immunological barrier providing the first line of defense against infection. Defects in EPCAM are a cause of hereditary non-polyposis colorectal cancer type 8 (HNPCC8) and diarrhea type 5 (DIAR5). EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Packaging :
Ambient
ALTnames :
Epithelial Cell Adhesion Molecule; Ep-CAM; Adenocarcinoma-Associated Antigen;Cell Surface Glycoprotein Trop-1; Epithelial Cell Surface Antigen; EpithelialGlycoprotein; EGP; Epithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signal Transducer 1; CD326; EPCAM
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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