product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Immunoglobulin Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
catalog :
CX71
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Cat# :
CX71
Type :
Recombinant Protein
name :
Recombinant Human Immunoglobulin Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
collection :
Immunity;Recombinant Proteins
sku :
CX71-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
Q8TDQ0
Background :
Hepatitis A virus cellular receptor 2（HAVCR2）is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnames :
Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3, FLJ14428,KIM-3,Tim-3,TIM3,TIMD3
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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