product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Mouse Platelet Endothelial Cell Adhesion Molecule/CD31/PECAM-1 (C-6His)
catalog :
CU23
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CU23
Product Name :
Recombinant Mouse Platelet Endothelial Cell Adhesion Molecule/CD31/PECAM-1 (C-6His)
Product Type :
protein
Accession Number :
Q08481
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
90
sku :
CU23-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Mouse Platelet Endothelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Glu18-Lys590 is expressed with a 6His tag at the C-terminus.
Expression :
Human Cells
Background :
Platelet endothelial cell adhesion molecule (PECAM-1, CD31) is a type I transmembrane glycoprotein adhesion molecule in the immunoglobulin superfamily. PECAM-1 is concentrated at cell junctions and is required for transendothelial migration (TEM). The extracellular domain (ECD) of PECAM-1 has ten potential N-linked glycosylation sites and six C2-type Ig-like domains, the first of which is critical for adhesion and extravasation. The cytoplasmic domain contains immunoregulatory tyrosine-based inhibitory and switch motifs (ITIM, ITSM) that mediate both inhibition and activation via phosphotyrosine-mediated engagement of SH2-containing signaling molecules. Expression is restricted to cells involved in circulation, especially endothelial cells, platelets, monocytes, neutrophils and lymphocyte subsets. PECAM-1 participates with other adhesion molecules in some functions, but is the critical molecule for TEM. Homotypic PECAM-1 adhesion in trans, combined with cycling of PECAM-1 to and from surface-connected endothelial cell vesicles, leads leukocytes across endothelial tight junctions.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
Packaging :
Ambient
ALTnames :
Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam1; Pecam
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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