product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Interleukin-5 Receptor Subunit Alpha/IL-5 Ra(C-Fc)
catalog :
CS69
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CS69
Product Name :
Recombinant Human Interleukin-5 Receptor Subunit Alpha/IL-5 Ra(C-Fc)
Product Type :
protein
Accession Number :
Q01344
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
150
sku :
CS69-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human Interleukin-5 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Asp21-Glu335 is expressed with a Fc tag at the C-terminus.
Expression :
Human Cells
Background :
Interleukin-5 Receptor alpha (IL-5R, CD125) is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology. Mature human IL-5 R consists of a 322 aa extracellular domain (ECD) with a WSxWS motif and a four cysteine motif, a 20 aa transmembrane segment, and a 58 aa cytoplasmic domain. Within the ECD, human IL-5R shares 71% aa sequence identity with mouse and rat IL-5 R. Alternate splicing of human IL-5 R generates soluble secreted forms which function as IL-5 antagonists. The high affinity receptor for IL-5 is a complex that consists of the ligand binding IL-5 R and the transmembrane common beta chain (betac/CD131) which is shared with the receptor complexes for IL-3 and GMCSF. IL-5 R binds IL-5 at low affinity and then associates with preformed betac oligomers to form the signaling competent receptor complex. IL-5 stimulation of CD34+ hematopoietic progenitor cells induces the up-regulation of transmembrane IL-5R followed by eosinophilic differentiation and activation.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
Packaging :
Ambient
ALTnames :
Interleukin-5 receptor subunit alpha; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125; IL5RA; IL5R
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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  • Affordable cost


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