product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)
catalog :
CS61
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Cat# :
CS61
Type :
Recombinant Protein
name :
Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)
collection :
Recombinant Proteins
sku :
CS61-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
Q9BZW8-2
Background :
Natural killer cell receptor 2B4 is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family.2B4 interacts with CD48, while other SLAM family proteins interact homophilically. Three additional splice variants of human 2B4 have deletions of the short region between the Ig-like domains, the second Ig-like domain, or a portion of the cytoplasmic tail.2B4 is expressed on all NK cells, γδ T cells, monocytes, some CD4+ and CD8+ T cells, and some dendritic cells. CD48 mediates 2B4+ cell interactions with nearly all hematopoietic cell types, including cells of the same type. 2B4/CD48 signaling cooperates with other receptor systems to either promote or inhibit NK and CD8+ T cell activation. The inhibitory activities are distinct from those of MHC I restricted inhibitory NK cell receptors. Ligation of 2B4 with antibodies or CD48 constructs can either directly trigger inhibitory signaling or disrupt an inhibitory interaction, leading to cellular activation. The inhibitory effect is associated with the long form of 2B4, while the activation is associated with the short form. 2B4 can also induce signaling through CD48.
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnames :
Natural killer cell receptor 2B4; NK cell activation-inducing ligand; NAIL; NKR2B4; h2B4; SLAM family member 4; SLAMF4; CD244; 2B4
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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