product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Fc gamma RIIa/FCGR2A/CD32a (C-6His,H131)
catalog :
CS35
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CS35
Product Name :
Recombinant Human Fc gamma RIIa/FCGR2A/CD32a (C-6His,H131)
Product Type :
protein
Accession Number :
P12318
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
95
sku :
CS35-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor II-A is produced by our Mammalian expression system and the target gene encoding Ala36-Ile218(His131Arg) is expressed with a 6His tag at the C-terminus.
Expression :
Human cells
Background :
Human FcgammaRs are divided into three classes designated FcgammaRI (CD64), FcgammaRII (CD32), and FcgammaRIII (CD16), which generate multiple isoforms, are recognized. The activating­ type receptor either has or associates non­covalently with an accessory subunit that has an immunoreceptor tyrosine­based activation motif (ITAM) in its cytoplasmic domain. FcgammaRI binds IgG with high affinity and functions during early immune responses, whereas FcgammaRII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses.Human CD32, also known as Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a), FcgammaRII A or FCGR2A Protein, is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Associated with an ITAM-bearing adapter subunit, FcRgamma, CD32a (FcgammaRII A) delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation, and cytokine production. The responses can be modulated by signals from the co-expressed inhibitory receptors such as Fcgamma RII B, and the strength of the signal is dependent on the ratio of expression of the activating and inhibitory receptors.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
Packaging :
Ambient
ALTnames :
Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD32; FCGR2A; FCG2; FCGR2A1; IGFR2
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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