product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant 2019-nCoV Papain-Like Protease
catalog :
CR77
quantity :
10 ug;50 ug;500 ug;1 mg
price :
158 USD
more info or order :
product information
Catalog Number :
CR77
Product Name :
Recombinant 2019-nCoV Papain-Like Protease
Product Type :
protein
Accession Number :
QHD43415.1
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
158 USD
sku :
CR77-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant 2019-nCoV Papain-like Protease is produced by our E.coli expression system and the target gene encoding Glu1564-Lys1878 is expressed.
Expression :
E. coli
Background :
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NSP3) section of the viral polypeptide. PLPro activity is required to process the viral polyprotein into functional, mature subunits; specifically, PLPro cleaves a site at the amino-terminus of the viral replicase region. In addition to its role in viral protein maturation, PLPro possesses a deubiquitinating and deISGylating activity. In vivo, this protease antagonizes innate immunity by inhibiting IRF3-induced production of type I interferons.
Endotoxin :
NA
Formulation :
Supplied as a 0.2 μm filtered solution of 20mM Tris-Hcl, 10 mM 2-Mercaptoethanol, 20%glycerol, pH 7.5.
Packaging :
Dry ice/ice packs
ALTnames :
Papain-like Protease; PLpro; PL-PRO; pp1a; Replicase polyprotein 1a
more info or order :
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
Our reagents, your discovery!
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
- Guaranteed quality
- Flexible and care
- Fast turnaround time
- Affordable cost
Our reagents, your discovery!