product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human CLDN18.1/Claudin-18/CLDN18 (N-8His)
catalog :
CR54
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
CR54
Product Name :
Recombinant Human CLDN18.1/Claudin-18/CLDN18 (N-8His)
Product Type :
protein
Accession Number :
P56856
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
250
sku :
CR54-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human CLDN18.1 is produced by our E.coli expression system and the target gene encoding Asp28-Leu76 is expressed with a 8His tag at the N-terminus.
Expression :
E. coli
Background :
Claudin-18(CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. IMAB362 (Claudiximab) is a monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 25mM NaCl, 0.1% Triton X-100, 10% glycerol, pH 8.0
Packaging :
Dry ice/ice packs
ALTnames :
Claudin-18; CLDN18
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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