This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Glypican-1/GPC1(N-6His)
catalog :
CP53
quantity :
10 ug;50 ug;500 ug;1 mg
price :
95 USD
product information
Cat# :
CP53
Type :
Recombinant Protein
name :
Recombinant Human Glypican-1/GPC1(N-6His)
collection :
Recombinant Proteins
sku :
CP53-10ug
price :
95 USD
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
P35052
Background :
The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 aa signal sequence, a 507 aa mature segment, and a 28 aa C-terminal prosegment. There are two potential N-linked and four potential O-linked sites for glycosylation or glycanation. There are potentially two heparan sulfate (HS) modifications on GPC1 that could contribute to a native molecular weight of approximately 200 kDa. Mature human GPC1 shares 91% aa identity with mature mouse GPC1. Cells known to express GPC1 include neurons, smooth and skeletal muscle cells, keratinocytes, osteoblasts, Schwann cells, immature dendritic cells, and tumor, plus tumorassociated vascular endothelial cells. The function of GPC1 is complex and varied. As a proteoglycan, it appears to make use of its HS adduct to impact select growth factor activity. This is accomplished by having juxtramembrane HS attachment sites, and a flexible, GPI-linkage.
Expression :
Human cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnames :
Glypican-1; GPC1
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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