product summary
Loading...
company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human IL-1 Receptor Type 2/IL-1R-2 (C-6His)
catalog :
CP30
quantity :
10 ug;50 ug;500 ug;1 mg
product information
Cat# :
CP30
Type :
Recombinant Protein
name :
Recombinant Human IL-1 Receptor Type 2/IL-1R-2 (C-6His)
collection :
Recombinant Proteins
sku :
CP30-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
P27930
Background :
Interleukin-1 receptor type 2 (IL1R2) belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1 receptor type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. IL1R2 is non-signaling receptor forIL1A, IL1B and IL1RN, reduces IL1B activities. IL1R2 serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Expression :
Human cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnames :
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

Every customer is our VIP:

Flat rate charge for gene synthesis, recombinant protein production
  • Guaranteed quality
  • Flexible and care
  • Fast turnaround time
  • Affordable cost


Our reagents, your discovery!