product summary
Loading...
company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Mesothelin/MSLN/CAK1/MPF (C-6His)
catalog :
CM52
quantity :
10 ug;50 ug;500 ug;1 mg
product information
Cat# :
CM52
Type :
Recombinant Protein
name :
Recombinant Human Mesothelin/MSLN/CAK1/MPF (C-6His)
collection :
Recombinant Proteins
sku :
CM52-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
Q13421
Background :
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnames :
Mesothelin, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, MSLN
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

Every customer is our VIP:

Flat rate charge for gene synthesis, recombinant protein production
  • Guaranteed quality
  • Flexible and care
  • Fast turnaround time
  • Affordable cost


Our reagents, your discovery!