product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Mouse Legumain/Asparaginyl Endopeptidase (C-6His)
catalog :
CJ83
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Cat# :
CJ83
Type :
Recombinant Protein
name :
Recombinant Mouse Legumain/Asparaginyl Endopeptidase (C-6His)
collection :
Enzymes;Recombinant Proteins
sku :
CJ83-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
O89017
Background :
Mouse Legumain,also known as LGMN, is a cysteine protease belonging to peptidase family C13 and is expressed in kidney and placenta abundantly. LGMN has a strict specificity for hydrolysis of asparaginyl bonds. It can also cleave aspartyl bonds slowly, especially under acidic conditions. The mammalian legumain is involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. It plays a role in the regulation of cell proliferation via its role in EGFR degradation. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Mammalian legumain is inhibited by iodoacetamide and maleimides. Legumain activation appears to be autocatalytic and can be triggered by acidic pH.
Expression :
Human Cells
Packaging :
Dry Ice/ice packs
Formulation :
Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,20% Glycerol,pH8.0.
ALTnames :
Legumain;Lgmn;Asparaginyl endopeptidase;Protease cysteine 1;Prsc1
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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