protein

Recombinant Mouse Tyrosine-Protein Kinase Receptor TYRO3/Dtk (C-mFc)

CJ47

10 ug;50 ug;500 ug;1 mg

Recombinant Mouse Tyrosine-Protein Kinase Receptor TYRO3/Dtk (C-mFc)

protein

P55144

10 ug;50 ug;500 ug;1 mg

50

CJ47-10ug

10ug;50ug;500ug;1mg

Recombinant Mouse Dtk is produced by our Mammalian expression system and the target gene encoding Ala31-Ser418 is expressed with a mFc tag at the C-terminus.

Human Cells

Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.

Less than 0.1 ng/ug (1 EU/ug)

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4

Ambient

Tyrosine-protein kinase receptor TYRO3,Tyro3,Etk2/tyro3,TK19-2,Tyrosine-protein kinase DTK,Tyrosine-protein kinase RSE,Tyrosine-protein kinase TIF