product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Mouse Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-6His)
catalog :
CJ10
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Cat# :
CJ10
Type :
Recombinant Protein
name :
Recombinant Mouse Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-6His)
collection :
Recombinant Proteins
sku :
CJ10-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
Q63994
Background :
Mouse myeloid cell surface antigen CD33(CD33) is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 contains one Ig-like C2-type domain and one Ig-like V-type domain. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia. CD33 is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML).
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
ALTnames :
CD33/Myeloid cell surface antigen CD33/Sialic acid-binding Ig-like lectin 3/Siglec-3/Siglec3
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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