product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human IA2/PTPRN (Met687-Gln979, N-6His)
catalog :
CH78
quantity :
10 ug;50 ug;500 ug;1 mg
product information
Cat# :
CH78
Type :
Recombinant Protein
name :
Recombinant Human IA2/PTPRN (Met687-Gln979, N-6His)
collection :
Recombinant Proteins
sku :
CH78-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
Q16849
Background :
Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Expression :
E. coli
Packaging :
Dry ice/Polar packs
Formulation :
Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
ALTnames :
Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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