protein

Recombinant Human CD39 (C-6His)

CA96

10 ug;50 ug;500 ug;1 mg

224 USD

Recombinant Human CD39 (C-6His)

protein

P49961

10 ug;50 ug;500 ug;1 mg

224 USD

CA96-10ug

10ug;50ug;500ug;1mg

Recombinant Human Ectonucleoside Triphosphate Diphosphohydrolase 1 is produced by our Baculovirus expression system and the target gene encoding Thr38-Val478 is expressed with a 6His tag at the C-terminus.

Baculovirus

Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1) is an integral membrane protein with an extracellular active site. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker. But it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1 hydrolyzes the β-andγ phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1 plays a role in the regulation of purinergic signaling. NTPDase-1 is involved in the processes of thromboregulation and vascular inflammation. The administration of soluble NTPDase-1 may have therapeutic applications for the treatment of some vascular and transplantation-associated diseases.

Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Supplied as a 0.2 μm filtered solution of 20mM Tris,500mM NaCl,10% Glycerol,pH 8.1.

Dry Ice/ice packs

Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39