product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Cynomolgus Sialic acid-binding Ig-like lectin 5/Siglec-5 (C-6His)
catalog :
CA56
quantity :
10 ug;50 ug;500 ug;1 mg
product information
Cat# :
CA56
Type :
Recombinant Protein
name :
Recombinant Cynomolgus Sialic acid-binding Ig-like lectin 5/Siglec-5 (C-6His)
sku :
CA56-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
A0A0B4J1D1
Background :
Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a 439aa extracellular domain (ECD) with three Ig-like domains, a transmembrane region and a cytoplasma tail. No Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH8.0.
ALTnames :
Sialic acid-binding Ig-like lectin 5; Siglec-5
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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