protein

Recombinant Human Galectin-3/LGALS3 (C-6His, Human Cells)

C846

10 ug;50 ug;500 ug;1 mg

Recombinant Protein

Recombinant Human Galectin-3/LGALS3 (C-6His, Human Cells)

Immunity;Recombinant Proteins

C846-10ug

10 ug;50 ug;500 ug;1 mg

P17931

Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.

Human Cells

Ambient

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 3mM DTT.

Galectin-3, Gal-3, 35 kDa Lectin, Carbohydrate-Binding Protein 35, CBP 35, Galactose-Specific Lectin 3, Galactoside-Binding Protein, GALBP, IgE-Binding Protein, L-31, Laminin-Binding Protein, Lectin L-29, Mac-2 Antigen, LGALS3, MAC2