product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human FAD-linked Sulfhydryl Oxidase ALR/GFER (N-6His)
catalog :
C700
quantity :
10 ug;50 ug;500 ug;1 mg
product information
Cat# :
C700
Type :
Recombinant Protein
name :
Recombinant Human FAD-linked Sulfhydryl Oxidase ALR/GFER (N-6His)
sku :
C700-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
P55789
Background :
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration. GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC). S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines.
Expression :
E. coli
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnames :
FAD-linked sulfhydryl oxidase ALR,GFER,Augmenter of liver regeneration,hERV1,Hepatopoietin,GFER,ALR,HERV1,HPO
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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