product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human GDNF Family Receptor α-1/GFRA1 (C-6His)
catalog :
C471
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
product information
Cat# :
C471
Type :
Recombinant Protein
name :
Recombinant Human GDNF Family Receptor α-1/GFRA1 (C-6His)
sku :
C471-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
P56159
Background :
Glial Cell Line-Derived Neurotrophic Factor Family Receptor α-1 (GDNFRα1) is a glycosylphosphatidylinositol (GPI) linked cell surface protein belonging to GDNF-family receptor α subtype which consists of at least four members. GFRα1and GFRα2 are the cognate co-receptor for the neurotrophic factor neurturin mediating the NRTN-induced autophosphorylation and activation of the RET tyrosine kinase receptor. Soluble GFRαs released enzymatically from the cell surface by phosphatidylinositol phospholipase C, as well as recombinantly produced soluble GFRα1, can also bind with high affinity to GDNF and trigger the activation of Ret tyrosine kinase. Human GFRα1 shares 93% amino acid identity with mouse GFRα1.The expression of the various GFRαs are differentially regulated in the central and peripheral nervous system, suggesting complementary roles for the GFRαs in mediating the activities of the GDNF family of neurotrophic factors.
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
ALTnames :
GDNF Family Receptor Alpha-1, GDNF Receptor Alpha-1, GDNFR-Alpha-1, GFR-Alpha-1, RET Ligand 1, TGF-Beta-Related Neurotrophic Factor Receptor 1, GFRA1, GDNFRA, RETL1, TRNR1
more info or order :
company information

Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
Our reagents, your discovery!
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
- Guaranteed quality
- Flexible and care
- Fast turnaround time
- Affordable cost
Our reagents, your discovery!
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