product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Brain-Specific Angiogenesis Inhibitor 3/BAI3 (C-6His)
catalog :
C431
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
Bon Opus Biosciences product webpage
product information
Cat# :
C431
Type :
Recombinant Protein
name :
Recombinant Human Brain-Specific Angiogenesis Inhibitor 3/BAI3 (C-6His)
collection :
Recombinant Proteins
sku :
C431-10ug
productOptionDescription1 :
10 ug;50 ug;500 ug;1 mg
Accession Number :
O60242
Background :
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98% aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.
Expression :
Human Cells
Packaging :
Ambient
Formulation :
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Thehalose, pH 7.2.
ALTnames :
Brain-Specific Angiogenesis Inhibitor 3, BAI3, KIAA0550
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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