product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human FGFR2IIIb (C-Fc)
catalog :
C13M
quantity :
10 ug;50 ug;500 ug;1 mg
price :
75 USD
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
C13M
Product Name :
Recombinant Human FGFR2IIIb (C-Fc)
Product Type :
protein
Accession Number :
P21802-3
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
75 USD
sku :
C13M-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human Fibroblast growth factor receptor 2 (IIIb) is produced by our Mammalian expression system and the target gene encoding Arg152-Glu378 is expressed with a Fc tag at the C-terminus.
Expression :
Human Cells
Background :
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. Only the alpha isoform has been identified for FGF R3 and FGF R4. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Packaging :
Ambient
ALTnames :
BFR-1; FGFR2IIIb; KGFR; CD332; FGF R2b; FGFR2 beta; FGFR2; FGFR2b
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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  • Fast turnaround time
  • Affordable cost


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