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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Mouse IL-17RE (C-6His)
catalog :
C13F
quantity :
10 ug;50 ug;500 ug;1 mg
price :
92 USD
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
C13F
Product Name :
Recombinant Mouse IL-17RE (C-6His)
Product Type :
protein
Accession Number :
Q8BH06
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
92 USD
sku :
C13F-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Mouse Interleukin-17 Receptor E is produced by our Mammalian expression system and the target gene encoding Ala115­His414 is expressed with a 6His tag at the C-terminus.
Expression :
Human Cells
Background :
Interleukin 17 Receptor E (IL 17 RE) is an approximately 70 kDa (predicted) transmembrane protein in the family of IL 17 receptors. IL 17 RE is expressed on keratinocytes, mucosal epithelial cells, Th17 cells, and gamma /δ T cells. It associates with the widely expressed IL 17 RA to form a heterodimeric receptor for IL-17C. IL-17C binds to IL 17 RE with high affinity and to IL 17 RA with low affinity. IL 17C expression is induced by inflammatory stimulation in colon and airway epithelial cells, keratinocytes, CD4+ T cells, macrophages, and dendritic cells. It is up regulated in various chronic inflammatory diseases including psoriasis, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). IL 17 RE is reciprocally down regulated in psoriatic lesions. The interaction of IL 17C with IL 17 RE promotes mucosal immunity through the induction of anti bacterial peptides and pro inflammatory cytokines and chemokines. IL 17C action supports the integrity of the colon epithelium following infection induced damage but also contributes to psoriatic skin thickening and the progression of arthritis. IL 17C is additionally up regulated in Th17 cell dependent autoimmunity. In this setting, it exacerbates disease severity by inducing Th17 cell production of IL 17A, IL 17F, IL 22, CCR6, and CCL20. The up regulation of IL 17 RE in hepatocellular carcinoma is associated with poor prognosis.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Packaging :
Ambient
ALTnames :
IL-17 RE; IL-17 receptor E; IL17RE; IL-17RE; interleukin 17 receptor E
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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