product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human MAdCAM-1 (C-6His)
catalog :
C12M
quantity :
10 ug;50 ug;500 ug;1 mg
price :
92 USD
product information
Catalog Number :
C12M
Product Name :
Recombinant Human MAdCAM-1 (C-6His)
Product Type :
protein
Accession Number :
Q4PKD0
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
92 USD
sku :
C12M-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human MADCAM1 is produced by our Mammalian expression system and the target gene encoding Gln19-Gln333 is expressed with a 6His tag at the C-terminus.
Expression :
Human Cells
Background :
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of proteins. The Ig domains of MAdCAM-1 are critical to alpha (4) beta (7) binding, and the mucin domain has activity in L Selectin binding. MAdCAM-1 expression is up-regulated by TNF-alpha and IL 1 beta. Mucosal addressin cell adhesion molecule (MAdCAM-1) plays a pivotal role in T-lymphocyte homing to the gut. MAdCAM 1 expression is also dramatically increased in chronic inflammatory and disease states, including inflammatory bowel disease (Crohn’s disease and ulcerative colitis), sclerosing cholangitis, and diabetes, and may play an important role in these conditions.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Packaging :
Ambient
ALTnames :
hMAdCAM-1; MACAM1; MAdCAM1; MAdCAM-1; mucosal addressin cell adhesion molecule 1
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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