product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Mouse PVRL2/Nectin-2/CD112 (C-Fc)
catalog :
C12C
quantity :
10 ug;50 ug;500 ug;1 mg
price :
75 USD
product information
Catalog Number :
C12C
Product Name :
Recombinant Mouse PVRL2/Nectin-2/CD112 (C-Fc)
Product Type :
protein
Accession Number :
P32507
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
75 USD
sku :
C12C-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Mouse Poliovirus Receptor-Related Protein 2 is produced by our Mammalian expression system and the target gene encoding Gln32-Gly351 is expressed with a Fc tag at the C-terminus.
Expression :
Human Cells
Background :
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens junctions, and exists on neurons, endothelial cells,epithelial cells and fibroblasts. CD112 has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 mediates cytotoxicity and cytokine secretion by T and NK cells. The costimulatory responses may be a critical component in allergic reactions and may therefore become targets for anti-allergic therapy.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Packaging :
Ambient
ALTnames :
Poliovirus Receptor-Related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B; HveB; Nectin-2; CD112; PVRL2; HVEB; PRR2
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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